List of contaminated cell lines

Author: twyv

August undefined, 2024

Web12 aug. 2011 · Of the cell lines commonly incorporated into xenograft models, ER-positive luminal A cell lines such as MCF-7 and T47D will only form tumours in the presence of oestrogen and, unsurprisingly, growth can be inhibited by anti-oestrogen therapy. Web15 apr. 2015 · Cell line misidentification, contamination and poor annotation affect scientific reproducibility. Here we outline simple measures to detect or avoid cross-contamination, present a framework for ...

List of contaminated cell lines - Wikipedia

Web4 nov. 2024 · Cell lines are widely used in research and for diagnostic tests and are often shared between laboratories. Lack of cell line authentication can result in the use of … Web26 jun. 2015 · The use of cross-contaminated cell lines has been a grave problem for decades (1 – 9) and has led to worldwide attempts to prevent further erosion (10 – 12).As biomedical research has blossomed, a steadily increasing proportion of reports involving human cell lines have been published by researchers in China (from 13.25% in 2009 to … gpt 4 launched

Database of Cross-Contaminated or Misidentified Cell Lines

WebThis database lists misidentified cell lines as well as cell lines that have been cross-contaminated. The following is from ICLAC’s Database of Known Misidentified Cell … Web1 nov. 2024 · HeLa cells are the first immortal human cell line. The cell line grew from a sample of cervical cancer cells taken from an African-American woman named Henrietta … Web27 feb. 2015 · But as those same cell lines are passed from person to person and lab to lab over many decades, they can be contaminated by other cells. The interlopers can outgrow the original cells, ultimately displacing the authentic culture completely. Based on his and other investigators' research, Korch estimates that about 20% of cell lines are ... gpt 4 microsoft edge

Meta-Research: Incidences of problematic cell lines are lower in …

(PDF) Cell Line Contamination and Misidentification - ResearchGate

WebThis database lists cell lines that are known to be cross-contaminated or otherwise misidentified. The authors take neither credit nor responsibility for any of the primary … gpt-4 newsWebRoutine testing of cell cultures is critical as cell lines frequently undergo misidentification, cross-contamination, and genetic drift. 1, 2 Cell authentication is also now required by the National Institutes of Health for grant funding and by a number of scientific journals, and the Food and Drug Administration requires validation of all … gpt-4 is coming next week

"Web21 jul. 2016 · Contaminated cell lines throw thousands of studies into question The Watchdogs Thousands of studies used the wrong cells, and journals are doing nothing By Ivan Oransky and Adam Marcus... " - List of contaminated cell lines

List of contaminated cell lines

Check your cultures! A list of cross-contaminated or misidentified …

Web5 sep. 2013 · Some reports may be difficult to find and to make these more accessible, we have compiled a list of known cross-contaminated cell lines. The list currently contains … WebIf it's a fairly typical contamination event, I found that they could usually be treated with either a different antibiotic (recommended; so if you typically use penicillin/streptomycin in your...

Did you know?

WebRetrospective studies on 500 human cell lines reveal that a minimum of eight core STR markers, D5S818, D13S317, D7S820, D16S539, vWA, TH01, TPOX, CSF1PO are … WebList of contaminated cell lines explained Many cell lines that are widely used for biomedical research have been overgrown by other, more aggressive cells. For …

WebFor most cell lines the appropriate level of containment is Level 2 requiring a class 2 microbiological safety cabinet. However, this may need to be increased to containment … Web17 apr. 2024 · Cell lines are used in life science research worldwide as biological surrogates. All cell lines are subject to major limitations when used as research tools, including (i) cross-contamination with other cells cultured in the same laboratory environment and (ii) evolution in vitro that renders a given cell line inappropriate as a …

WebPublished data from researchers and testing performed during ATCC accessioning have established that these cell lines are contaminated with HeLa cells. These findings are … WebMany cell lines that are widely used for biomedical research have been overgrown by other, more aggressive cells. For example, supposed thyroid lines were actually melanoma cells, supposed prostate tissue was actually bladder cancer, and supposed normal uterine cultures were actually breast cancer. This is a list of cell lines that have been cross …

Web29 jan. 2024 · For example, the problematic list includes cases where a cell line is ‘partially contaminated’, which does not affect cells purchased from, say, a stock center. The list …

Web20 sep. 2010 · Contaminated or misidentified cell lines have also been listed on the websites of individual cell banks. To make it easier to check for these references, a … gpt4 image to textWeb12 okt. 2024 · table lists all cell lines in the ICLAC database and the number of articles in the primary and. ... A list of cross-contaminated or misidentified cell lines. Int J Cancer. 2010; 127(1):1–8. gpt-4 microsoftWebFirst, it is important to check the literature, looking for previous work on cross-contamination. Some reports may be difficult to find and to make these more accessible, we have … gpt 4 newsWeb15 apr. 2024 · Many types of human cells are cataloged in cell banks for research and drug testing studies: jcam1.6 human lymphocytes. J82 human bladder cells. kmst-6 human skin cells. hela229 human cervical cells. … gpt-4 number of parametersWebCell line Extant? Cell Type Real cell line Real cell type Reference; 207: Extant? pre-B cell leukemia: REH or CCRF-CEM: pre-B cell or T cell leukemia: MacLeod et al. (1999) … gpt-4 is as astonishing as it is unnervingWeb9 sep. 2013 · After nine years in print, Nature Methods today published its first retraction; one that could have been prevented by cell line authentication. ... A continuously curated list of more than 400 misidentified cell lines (Database of Cross-Contaminated or Misidentified Cell Lines, Version 7.1) gpt4 number of parametersWeb170 rijen · The NCI-60 cancer cell line panel is a group of 60 human cancer cell lines used by the National Cancer Institute (NCI) for the screening of compounds to detect potential … gpt4 microsoft edge