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WebKeywords: end-stage renal disease; dialysis; myoclonus; morphine; opioid rotation. INTRODUCTION AND PATIENT PROFILE he patient presented is a 59-year-old African-American man with end-stage renal disease (ESRD). ESRD is a subset of chronic kidney disease (CKD) stage 5, in which patients undergo dialysis or receive a kidney transplant. WebMHRA/CHM advice: Prescribing medicines in renal impairment: using the appropriate estimate of renal function to avoid the risk of adverse drug reactions (October 2024) For cases where CrCl, calculated using the Cockcroft and Gault formula, should be used to determine renal dose adjustments, see Important: dosage adjustment advice in the BNF, … richard hulsey obituary
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