Small g protein signaling modulator 2
WebbRoles of described genes in G protein signaling [small G protein signaling modulator 2 (SGSM2), MAP kinase activating death domain (MADD), TBC1 domain family member 30 (TBC1D30), and KN motif and ... WebbSGSM3, small G protein signaling modulator 3, DKFZp761D051, MAP, RUSC3, RUTBC3, RUN and SH3 containing 3, RUN and TBC1 domain containing 3, merlin binding protein, merlin-associated protein, small G protein signaling modulator 3 protein Gene ID ...
Small g protein signaling modulator 2
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Webb10 juni 2024 · G-protein-signaling modulator 2 (GPSM2) is widely recognized as a determinant of mitotic spindle orientation. However, its role in cancer, especially NSCLC, remains uncertain. In this study, we found that GPSM2 was downregulated in NSCLC tissues and was correlated with a poor prognosis. WebbG-protein-signaling modulator 1 (GPSM1), an accessory protein which activates heterotrimeric G-protein signaling, exhibits a genetic association with type 2 diabetes.
WebbG-protein-signaling modulator 2, also called LGN for its 10 Leucine-Glycine-Asparagine repeats, is a protein that in humans is encoded by the GPSM2 gene. [5] [6] [7] Function [ … Webb25 okt. 2013 · Dexras1 and RHES, monomeric G proteins, are members of small GTPase family that are involved in modulation of pathophysiological processes. Dexras1 and RHES levels are modulated by hormones and Dexras1 …
Webb23 jan. 2024 · G-protein-signaling modulator 2 (GPSM2) is an important factor that regulates the localization and mitotic spindle pole orientation of cells. 13 Fukukawa et al … WebbThe function of small G protein signalling modulators (SGSM1/2/3) in cancer remains unknown. Our findings demonstrated that SGSM2 is a plasma membrane protein that strongly interacted with E-cadherin/β-catenin. SGSM2 downregulation enhanced the phosphorylation of focal adhesion kinase (FAK; Y576/577 …
Webb9 mars 2024 · Small G protein signaling modulators 2 (SGSM2) belongs to a newly identified protein group that contributes to numerous cancer progression. However, its role in TC remains unknown. The...
Webb15 aug. 2014 · G protein signaling modulator-3 (GPSM3), also known as G18 or AGS4, is a member of a family of proteins containing one or more copies of a small regulatory … grand rapids mi leaf pick upWebb28 mars 2024 · Small G proteins in the superfamily have a common 20 K molecular weight catalytic (GTPase) domain with 5 alpha helices, 6 beta strands, and connecting loops. The small G proteins are "active" in the GTP-bound form. Hydrolysis of GTP to GDP causes the protein to become inactive. Figure 28.5. 1 shows the domain structures of small G … grand rapids mi hotels with in room jacuzziWebbmammalian protein found in Homo sapiens. Small G protein signaling modulator 2 (Q21134819) From Wikidata ... chinese new year noodle recipeWebbPhenotypes & Models Summary Gene: Sgsm2 (small G protein signaling modulator 2) Mus musculus Add Watcher Analyze General Array IDs Annotation Click to see Annotation Detail View Disease Annotations Click to see Annotation Detail View Gene-Chemical Interaction Annotations Click to see Annotation Detail View grand rapids mi movie theatersWebb10 jan. 2024 · G-protein-coupled receptors (GPCRs) are the largest class of signaling receptors that are most frequently targeted by therapeutic drugs. Allosteric modulators bound to GPCRs at allosteric sites provide the potential for differential selectivity and improved safety compared with traditional orthosteric ligands. chinese new year north carolinaWebbSMALL G PROTEIN SIGNALING MODULATOR 2; SGSM2 Alternative titles; symbols KIAA0397 HGNC Approved Gene Symbol: SGSM2 Cytogenetic location: 17p13.3 … grand rapids mi newspaper obituariesWebb25 nov. 2024 · G-protein-signaling modulator 1 (GPSM1) exhibits strong genetic association with Type 2 diabetes (T2D) and Body Mass Index in population studies. … grand rapids mi newspaper local